Sigma.P4707-50ML Poly-L-LYSINE SOLUTION 50ml

     Components
     Poly-L-lysine is a positively charged amino acid polymer with approximately one HBr per lysine residue. The hydrobromide

     allows the poly-L-lysine to be in a crystalline form soluble in water. A small amount of product may be found in the beta

     structure because the HBr interferes with hydrogen bonding between amino and either the carboxyl groups or N or O

     containing moieties.

     Application

     Poly-L-lysine polymers can be used in promoting cell adhesion to solid substrates, conjugation to methotrexate for increased

     drug transport, microencapsulation of islets, cell microencapsulation technology, microarray glass slide coating, and

     chromosomal preparations. Lower molecular weight poly-L-lysine (30,000-70,000) is less viscuous in solution, but higher

     molecular weight versions provide more attachment sites per molecule.

     • Poly-L-lysine coated glass coverslips have been used for mounting samples for scanning electron microscopy.[1]
     • Poly-L-lysine coated wells were used for trapping of PC-12 cells on electrodes.[2]
     • Poly-L-lysine-coated borosilicate glass slides were used for the seeding of viral vector-transduced cells.[3]