Thermo.11-9668-82 Anti-Mouse Ly-6G (Gr-1) FITC 100ug

     货品编号：  Thermo.11-9668-82     
     品牌：  Thermo
     品名：  Anti-Mouse Ly-6G (Gr-1) FITC  
     规格：  100ug
   
     产品描述：  

     Description: The monoclonal antibody 1A8-Ly6g reacts with mouse Ly-6G, which is also known as Gr-1. Ly-6G is a 25-kDa

     GPI protein expressed exclusively by neutrophils. Studies suggest an important role in neutrophil infiltration, recruitment and

     migration. Ly-6G associates with B2 integrins CD11a and CD11b and can attenuate B2 integrin expression and function.

     The ligand for Ly-6G is currently unknown.

     Unlike the RB6-8C5 antibody, 1A8-Ly6g is reported to only bind to Ly-6G found on neutrophils. Moreover, 1A8-Ly6g has been

     used to deplete neutrophils and reported to have antagonist activity.

     Applications Reported: This 1A8-Ly6g antibody has been reported for use in flow cytometric analysis.

     Applications Tested: This 1A8-Ly6g antibody has been tested by flow cytometric analysis of mouse splenocytes. This can be

     used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a

     final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended

     that the antibody be carefully titrated for optimal performance in the assay of interest.